Genome-Wide Association Study

Introduction

A large number of genetic variation markers (usually SNPs) were obtained based on high-throughput sequencing. Genotypes and observable traits (phenotypes) were analyzed at population level, and genes related to trait variation were excavated.

Data analysis Pipeline

 

 

Advantages and Application Areas

Highly experienced: We have completed major resequencing projects about GWAS, and our data has been published in top-tier journals.

Largest sequencing capacity: We have Illumina, PacBio and Nanopore sequencing capacities in the world, and use indels ,SV to analysisallowing us to provide high quality data, fast turnaround, and affordable prices.

Biomarker Successful Cases

[1] Whole-genome resequencing reveals Brassica napus origin and genetic loci involved in its improvement[J]. Nature Communications2019IF=12.353.

[2] Whole-genome resequencing of a world-wide collection of rapeseed accessions reveals genetic basis of their ecotype divergence[J]. Molecular Plant2019IF=9.326.

[3]Genome-wide association study discovered candidate genes of Verticillium wilt resistance in upland cotton (Gossypium hirsutum L.)[J]. Plant Biotechnology Journal2017IF=6.305.

[4] Loci and candidate gene identification for resistance to Sclerotinia sclerotiorum in soybean(Glycine max L.Merr.) via association and linkage maps[J]. The Plant Journal2015IF=5.775.

[5] Genome-Wide Association Study and Transcriptome Analysis Provide New Insights into the White/Red Earlobe Color Formation in Chicken[J].Cellular Physiology and Biochemistry2018IF=5.104.